"The process whose specific outcome is the progression of the liver over time, from its formation to the mature structure. The liver is an exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes [goid 1889] [evidence ISS]; The synthesis of either RNA on a template of DNA or DNA on a template of RNA [goid 6350] [evidence IEA]; Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter [goid 6357] [pmid 16255782] [evidence IDA]; Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat [goid 6955] [evidence ISS]; The process whereby a precursor cell type acquires the specialized features of a B cell [goid 30183] [evidence ISS]; The directed killing of a target cell by a natural killer cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors [goid 42267] [evidence ISS]; The process by which a myeloid precursor cell acquires specializes features of an erythrocyte without a nucleus, as found in mammals [goid 43353] [evidence ISS]; Any process that stops, prevents or reduces the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription [goid 43433] [pmid 7501458] [evidence ISS]; Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interferon-gamma [goid 45078] [evidence ISS]; Any process that activates or increases the frequency, rate or extent of DNA repair [goid 45739] [pmid 16255782] [evidence IEP]; Any process that activates or increases the frequency, rate or extent of activity of a transcription factor, any factor involved in the initiation or regulation of transcription [goid 51091] [pmid 7665092] [evidence TAS]"