"The chemical reactions and pathways involving proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans [goid 6029] [pmid 11574464] [evidence IDA]; The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages [goid 6954] [evidence IEA]; Any process that stops, prevents or reduces the frequency, rate or extent of angiogenesis [goid 16525] [pmid 11591732] [evidence IDA]; Any process that modulates the frequency, rate or extent of activity of any TGF-beta receptor signaling pathway [goid 17015] [pmid 11591732] [evidence IDA]; The chemical reactions and pathways resulting in the formation of the cytokine lymphotoxin A [goid 42109] [pmid 11591732] [evidence IDA]; Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-2 [goid 45076] [pmid 11591732] [evidence IDA]; Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-6 [goid 45408] [pmid 11574464] [evidence IDA]; Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-8 [goid 45414] [pmid 11574464] [evidence IDA]; Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of granulocyte macrophage colony-stimulating factor [goid 45423] [pmid 11574464] [evidence IDA]; The process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate [goid 51216] [pmid 11574464] [evidence IDA]"