"The chemical reactions and pathways involving sphingosine (sphing-4-enine), trans-D-erytho-2-amino-octadec-4-ene-1,3-diol, a long chain amino diol sphingoid base that occurs in most sphingolipids in animal tissues [goid 6670] [pmid 10751414] [evidence TAS]; A process which directly inhibits any of the steps required for cell death by apoptosis [goid 6916] [pmid 10947957] [evidence TAS]; The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand [goid 7186] [pmid 12441135] [evidence TAS]; The initiation of the activity of the inactive enzyme protein kinase C as the result of a series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand [goid 7205] [evidence IEA]; A series of reactions within the cell that occur as a result of a single trigger reaction or compound [goid 7242] [pmid 10947957] [evidence TAS]; A series of molecular signals in which a cell uses calcium ions to convert an extracellular signal into a response [goid 19722] [pmid 10947957] [evidence IDA]; Any process that activates or increases the frequency, rate or extent of cell growth [goid 30307] [pmid 12441135] [evidence IDA]; Any process that activates or increases the frequency, rate or extent of cell migration [goid 30335] [pmid 12441135] [evidence IDA]; Any process that activates or increases angiogenesis [goid 45766] [pmid 12441135] [evidence IDA]; Any process that activates or increases the rate or extent of progression through the mitotic cell cycle [goid 45931] [pmid 12441135] [evidence IDA]; Any process that activates or increases the frequency, rate or extent of smooth muscle contraction [goid 45987] [pmid 12847068] [evidence IDA]; The chemical reactions and pathways resulting in the breakdown of sphingoids, any of a class of compounds comprising sphinganine and its homologues and stereoisomers, and derivatives of these compounds [goid 46521] [pmid 10863092] [evidence NAS]; Any process that activates or increases the frequency, rate or extent of multiplication or reproduction of fibroblast cells [goid 48146] [pmid 15623571] [evidence IDA]; The initiation of the activity of the inactive enzyme protein kinase C as the result of a series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand [goid 7205] [evidence IEA]; The initiation of the activity of the inactive enzyme protein kinase C as the result of a series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand [goid 7205] [evidence IEA]"