"Passage through a cell cycle control point late in G1 phase of the mitotic cell cycle just before entry into S phase; in most organisms studied, including budding yeast and animal cells, passage through start normally commits the cell to progressing through the entire cell cycle [goid 7089] [evidence IEA]; The process by which one or more ubiquitin moieties are added to a protein [goid 16567] [evidence IEA]; The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds [goid 30163] [evidence IEA]; Any process that stops, prevents or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter [goid 122] [evidence ISS]; Any process that stops, prevents or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter [goid 122] [pmid 9271120] [evidence IDA]; The aggregation, arrangement and bonding together of a set of components to form a protein complex [goid 6461] [pmid 12915590] [evidence IDA]; The aggregation, arrangement and bonding together of a set of components to form a protein complex [goid 6461] [pmid 10608892] [evidence IDA]; The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin moiety, or multiple ubiquitin moieties, to the protein [goid 6511] [evidence IEA]; Passage through a cell cycle control point late in G1 phase of the mitotic cell cycle just before entry into S phase; in most organisms studied, including budding yeast and animal cells, passage through start normally commits the cell to progressing through the entire cell cycle [goid 7089] [evidence IEA]; Any process that stops, prevents or reduces the rate or extent of cell proliferation [goid 8285] [pmid 7791904] [evidence TAS]; The process by which one or more ubiquitin moieties are added to a protein [goid 16567] [evidence IEA]; The process by which one or more ubiquitin moieties are added to a protein [goid 16567] [pmid 9450543] [evidence IDA]; The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds [goid 30163] [evidence IEA]; Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds [goid 42176] [pmid 9153395] [evidence IDA]; Any process by which an organism has an effect on an organism of a different species [goid 44419] [evidence IEA]"