"The process whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure. The skeleton is the bony framework of the body in vertebrates (endoskeleton) or the hard outer envelope of insects (exoskeleton or dermoskeleton) [goid 1501] [evidence IEA]; The process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate [goid 2063] [evidence IEA]; Upregulation of the activity of a caspase, any of a group of cysteine proteases involved in apoptosis [goid 6919] [evidence IEA]; The process of apoptosis in cells infected with a virus [goid 6926] [evidence IEA]; The series of molecular signals generated by the accumulation of normal or misfolded proteins in the endoplasmic reticulum and leading to activation of transcription by NF-kappaB [goid 6983] [pmid 10677345] [evidence IDA]; The series of molecular signals generated by the accumulation of normal or misfolded proteins in the endoplasmic reticulum and leading to activation of transcription by NF-kappaB [goid 6983] [pmid 11907036] [evidence IDA]; A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus [goid 6986] [evidence IEA]; A process that is carried out at the cellular level which results in the formation, arrangement of constituent parts, or disassembly of the endoplasmic reticulum [goid 7029] [evidence IEA]; Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA [goid 17148] [pmid 12086964] [evidence TAS]; A series of molecular signals in which a cell uses calcium ions to convert an extracellular signal into a response [goid 19722] [evidence IEA]; The regulated release of proinsulin from secretory granules (B granules) in the B cells of the pancreas; accompanied by cleavage of proinsulin to form mature insulin [goid 30073] [evidence IEA]; The deposition of calcium phosphate in bone tissue [goid 30282] [evidence IEA]; The series of molecular signals generated as a consequence of the presence of unfolded proteins in the endoplasmic reticulum (ER) or other ER-related stress; results in changes in the regulation of transcription and translation [goid 30968] [pmid 10677345] [evidence IDA]; The series of molecular signals generated as a consequence of the presence of unfolded proteins in the endoplasmic reticulum (ER) or other ER-related stress; results in changes in the regulation of transcription and translation [goid 30968] [pmid 11907036] [evidence IDA]; The process whose specific outcome is the progression of the endocrine pancreas over time, from its formation to the mature structure. The endocrine pancreas is made up of islet cells that produce insulin, glucagon and somatostatin [goid 31018] [pmid 12086964] [evidence IMP]; Any process that stops, prevents or reduces the frequency, rate or extent of the formation of a myelin sheath around nerve axons [goid 31642] [evidence IEA]; Any process that stops, prevents or reduces the rate of translation initiation as a result of a stimulus indicating the organism is under stress [goid 32057] [pmid 12086964] [evidence TAS]; Any process that stops, prevents or reduces the rate of translation initiation as a result of a stimulus indicating the organism is under stress [goid 32057] [pmid 10677345] [evidence TAS]; Any process that activates or increases the frequency, rate or extent of protein binding [goid 32092] [evidence IEA]; The phosphorylation by a protein of one or more of its own amino acid residues, or residues on an identical protein [goid 46777] [pmid 10026192] [evidence IDA]; The phosphorylation by a protein of one or more of its own amino acid residues, or residues on an identical protein [goid 46777] [pmid 12086964] [evidence IMP]; The phosphorylation by a protein of one or more of its own amino acid residues, or residues on an identical protein [goid 46777] [pmid 11907036] [evidence IDA]; The series of molecular signals generated as a consequence of the insulin-like growth factor receptor binding to one of its physiological ligands [goid 48009] [evidence IEA]; The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer [goid 51260] [pmid 11907036] [evidence IMP]"