"Any process that modulates the frequency, rate or extent of DNA-dependent transcription [goid 6355] [evidence IEA]; Any process that stops, prevents or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter [goid 122] [evidence IEA]; The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification [goid 6694] [pmid 9384387] [evidence IDA]; A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation) [goid 6950] [evidence IEA]; The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis [goid 7283] [evidence IEA]; Any process by which a protein is transported to, or maintained in, a specific location [goid 8104] [pmid 11875111] [evidence IDA]; Any process that stops, prevents or reduces the frequency, rate or extent of transcription [goid 16481] [evidence IEA]; The progression of the hypothalamus region of the forebrain, from its initial formation to its mature state [goid 21854] [pmid 15464421] [evidence NAS]; The progression of the pituitary gland over time from its initial formation until its mature state. The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands [goid 21983] [pmid 15464421] [evidence NAS]; The specification of male sex of an individual organism [goid 30238] [evidence IEA]; The process whose specific outcome is the progression of the adrenal gland over time, from its formation to the mature structure. This gland can either be a discrete structure located bilaterally above each kidney, or a cluster of cells in the head kidney that perform the functions of the adrenal gland. In either case, this organ consists of two cells types, aminergic chromaffin cells and steroidogenic cortical cells [goid 30325] [evidence IEA]; The process whose specific outcome is the progression of the adrenal gland over time, from its formation to the mature structure. This gland can either be a discrete structure located bilaterally above each kidney, or a cluster of cells in the head kidney that perform the functions of the adrenal gland. In either case, this organ consists of two cells types, aminergic chromaffin cells and steroidogenic cortical cells [goid 30325] [pmid 7990953] [evidence IMP]; Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of any steroid hormone receptor signaling pathway [goid 33144] [pmid 11875111] [evidence IDA]; The process whereby a relatively unspecialized cell acquires specialized structural and/or functional features of a Leydig cell. A Leydig cell is a testosterone-secreting cell in the interstitial area, between the seminiferous tubules, in the testis [goid 33327] [evidence IEA]; Any process that stops, prevents or reduces the frequency, rate or extent of cell differentiation [goid 45596] [evidence IEA]; The process whereby a relatively unspecialized cell acquires specialized structural and/or functional features of a Sertoli cell. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules [goid 60008] [evidence IEA]"