"The directed movement of copper (Cu) ions into, out of, within or between cells [goid 6825] [evidence IEA]; The directed movement of mercury (Hg) ions into, out of, within or between cells [goid 15694] [evidence IEA]; The directed movement of metal ions, any metal ion with an electric charge, into, out of, within or between cells [goid 30001] [evidence IEA]; The directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells, or within a multicellular organism [goid 6810] [evidence IEA]; The directed movement of copper (Cu) ions into, out of, within or between cells [goid 6825] [evidence IEA]; The directed movement of mercury (Hg) ions into, out of, within or between cells [goid 15694] [evidence IEA]; The directed movement of metal ions, any metal ion with an electric charge, into, out of, within or between cells [goid 30001] [evidence IEA]; The process whose specific outcome is the progression of the blood vessel over time, from its formation to the mature structure. The blood vessel is the vasculature carrying blood [goid 1568] [evidence ISS]; The reorganization or renovation of existing blood vessels [goid 1974] [evidence ISS]; Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis [goid 2082] [evidence ISS]; The chemical reactions and pathways involving tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid [goid 6568] [evidence ISS]; The directed movement of charged atoms or small charged molecules into, out of, within or between cells [goid 6811] [evidence IEA]; The regulation of the levels, transport, and metabolism of copper ions within a cell or between a cell and its external environment [goid 6878] [pmid 16397091] [evidence IMP]; A process that is carried out at the cellular level which results in the formation, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphology and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components [goid 7005] [evidence ISS]; The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions [goid 7626] [evidence ISS]; The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation [goid 8152] [evidence IEA]; Any process that reduce or remove the toxicity of copper ion. These include transport of copper away from sensitive areas and to compartments or complexes whose purpose is sequestration of copper ion [goid 10273] [evidence ISS]; The directed movement of copper ions into a cell or organelle [goid 15677] [evidence ISS]; The directed movement of mercury (Hg) ions into, out of, within or between cells [goid 15694] [evidence IEA]; The modification of peptidyl-lysine [goid 18205] [evidence ISS]; Any process involved in removing superoxide radicals (O2-) from a cell or organism, e.g. by conversion to dioxygen (O2) and hydrogen peroxide (H2O2) [goid 19430] [evidence ISS]; The process whereby neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar Purkinje cell. Differentiation includes the processes involved in commitment of a neuroblast to a Purkinje cell fate. A Purkinje cell is an inhibitory GABAergic neuron found in the cerebellar cortex that projects to the deep cerebellar nuclei and brain stem [goid 21702] [evidence ISS]; The progression of a pyramidal neuron from its initial formation to its mature state [goid 21860] [evidence ISS]; The process whose specific outcome is the progression of a neuron whose cell body is located in the central nervous system, from initial commitment of the cell to a neuronal fate, to the fully functional differentiated neuron [goid 21954] [evidence ISS]; The directed movement of metal ions, any metal ion with an electric charge, into, out of, within or between cells [goid 30001] [evidence IEA]; Any process that determines the size and arrangement of collagen fibrils within an extracellular matrix [goid 30199] [evidence ISS]; The process by which the anatomical structures of the hair follicle are generated and organized [goid 31069] [evidence ISS]; The process whereby a relatively unspecialized thymocyte acquires specialized features of a T-helper cell [goid 42093] [evidence ISS]; The chemical reactions and pathways involving epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine [goid 42414] [evidence ISS]; The chemical reactions and pathways involving norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine [goid 42415] [evidence ISS]; The chemical reactions and pathways involving dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline [goid 42417] [evidence ISS]; The chemical reactions and pathways involving serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties [goid 42428] [evidence ISS]; The deposition or aggregation of coloring matter in an organism, tissue or cell [goid 43473] [evidence ISS]; Any process that modulates the occurrence or rate of cell death by apoptosis in the nervous system. It may stop or prevent or reduce the rate of cell death by apoptosis and it is activated by stress to counteract death signals in central nervous systems. Different neuroprotective mechanisms may be activated to combat distinct types of cellular stress, ERK pathway is one of several neuroprotective mechanisms and it is a model system to study neuronal apoptosis, which may contribute to several neurodegenerative diseases and aging-related neuron loss [goid 43526] [evidence ISS]; The process whose specific outcome is the progression of the skin over time, from its formation to the mature structure. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner vascular dermis (cutis, corium or true skin) composed mostly of connective tissue [goid 43588] [evidence ISS]; Assembly of the extracellular matrix fibers that enables the matrix to recoil after transient stretching [goid 48251] [evidence ISS]; The process whose specific outcome is the progression of the alveolus over time, from its formation to the mature structure. The alveolus is a sac for holding air in the lungs; formed by the terminal dilation of air passageways [goid 48286] [evidence ISS]; Any process that stops, prevents or reduces the frequency, rate or extent of activity of a metalloenzyme. A metalloenzyme is any enzyme that contains metal [goid 48553] [evidence ISS]; Any process that activates, maintains or increases the rate activity of a metalloenzyme. A metalloenzyme is any enzyme that contains metal [goid 48554] [evidence ISS]; The process by which the anatomical structures of neurites are generated and organized. Morphogenesis pertains to the creation of form. A neurite is any process extending from a neural cell, such as axons or dendrites [goid 48812] [evidence ISS]; The process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate [goid 51216] [evidence ISS]; Any process that activates or increases the frequency, rate or extent of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered [goid 51353] [pmid 11092760] [evidence IDA]; The chemical reactions and pathways resulting in the formation of elastin, a fibrous glycoprotein found in elastic tissues such as the walls of arteries [goid 51542] [evidence ISS]; The directed movement of copper ions out of a cell or organelle [goid 60003] [evidence ISS]"