"Cascade of at least three protein kinase activities culminating in the phosphorylation and activation of a MAP kinase. MAPKKK cascades lie downstream of numerous signaling pathways [goid 165] [evidence IEA]; The process whose specific outcome is the progression of the ureteric bud over time, from its formation to the mature structure [goid 1657] [evidence IEA]; The characteristic movement of cells from the dorsal ridge of the neural tube to a variety of locations in a vertebrate embryo [goid 1755] [evidence IEA]; The morphogenesis of an embryonic epithelium into a tube-shaped structure [goid 1838] [evidence IEA]; The process of introducing a phosphate group on to a protein [goid 6468] [pmid 7824936] [evidence TAS]; The attachment of an adhesion molecule in one cell to an identical molecule in an adjacent cell [goid 7156] [evidence IEA]; The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately effecting a change in the functioning of the cell [goid 7165] [pmid 7824936] [evidence TAS]; The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state [goid 7399] [evidence IEA]; The process whose specific outcome is the progression of the posterior midgut over time, from its formation to the mature structure [goid 7497] [pmid 8114939] [evidence TAS]; A developmental process, independent of morphogenetic (shape) change, that is required for a neuron to attain its fully functional state [goid 42551] [evidence IEA]; The process whose specific outcome is the progression of the enteric nervous system over time, from its formation to the mature structure. The enteric nervous system is composed of two ganglionated neural plexuses in the gut wall which form one of the three major divisions of the autonomic nervous system. The enteric nervous system innervates the gastrointestinal tract, the pancreas, and the gall bladder. It contains sensory neurons, interneurons, and motor neurons. Thus the circuitry can autonomously sense the tension and the chemical environment in the gut and regulate blood vessel tone, motility, secretions, and fluid transport. The system is itself governed by the central nervous system and receives both parasympathetic and sympathetic innervation [goid 48484] [evidence IEA]"