"The directed movement of a protein from the cytoplasm to the nucleus [goid 6606] [pmid 10924506] [evidence NAS]; The chemical reactions and pathways involving dioxygen (O2), or any of the reactive oxygen species, e.g. superoxide anions (O2-), hydrogen peroxide (H2O2), and hydroxyl radicals (-OH) [goid 6800] [pmid 16826196] [evidence IMP]; The directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells, or within a multicellular organism [goid 6810] [evidence IEA]; A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle the cell and result in cell death. Apoptosis begins internally with condensation and subsequent fragmentation of the cell nucleus (blebbing) while the plasma membrane remains intact. Other characteristics of apoptosis include DNA fragmentation and the exposure of phosphatidyl serine on the cell surface [goid 6915] [evidence IEA]; Any process induced by extracellular signals that directly activates any of the steps required for cell death by apoptosis [goid 8624] [pmid 10924506] [evidence IDA]; Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA [goid 17148] [pmid 12867595] [evidence IDA]; A process whereby a series of electron carriers operate together to transfer electrons from donors to any of several different terminal electron acceptors to generate a transmembrane electrochemical gradient [goid 22900] [evidence IEA]; The morphological and physiological alterations undergone by the nucleus during apoptosis [goid 30262] [pmid 10924506] [evidence IDA]; Any process that stops, prevents or reduces the frequency, rate or extent of cell growth [goid 30308] [pmid 16826196] [evidence IMP]; Any process that stops, prevents or reduces the frequency, rate or extent of cell growth [goid 30308] [pmid 10924506] [evidence IDA]; Any process that stops, prevents or reduces the frequency, rate or extent of DNA-dependent transcription [goid 45892] [pmid 12867595] [evidence IDA]"